MACHINE LEARNING FOR EXPLORING NEUROPHYSIOLOGICAL FUNCTIONALITY IN MULTIPLE SCLEROSIS BASED ON TRIGEMINAL AND HAND BLINK REFLEXES

Machine learning for exploring neurophysiological functionality in multiple sclerosis based on trigeminal and hand blink reflexes

Abstract Brainstem dysfunctions are very common in Multiple Sclerosis (MS) and are a critical predictive factor for future disability.Brainstem functionality can be explored with blink sennheiser ba 70 reflexes, subcortical responses consisting in a blink following a peripheral stimulation.Some reflexes are already employed in clinical practice, su

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Antithrombotic effect of repeated doses of the ethanolic extract of local olive (Olea europaea L.) leaves in rabbits

The incidence of arla eagle rock thromboembolic diseases is increasing, and they are a major cause of mortality and morbidity worldwide.Mediterranean diet is known for its high content of olive products, especially olive oil, which has known cardiovascular health benefits, including those on blood pressure, cholesterol level, and thrombogenesis.All

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A versatile method to design stem-loop primer-based quantitative PCR assays for detecting small regulatory RNA molecules.

Short regulatory RNA-s have been identified as key regulators of gene expression in eukaryotes.They have been involved in the regulation of both physiological and pathological processes such as embryonal development, immunoregulation and cancer.One of their relevant characteristics is their high stability, which makes them excellent candidates for

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Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers

Abstract Toxic protein aggregates can spread among neurons to promote human neurodegenerative disease pathology.We found that in C.elegans touch neurons intermediate filament proteins IFD-1 and IFD-2 associate with aggresome-like organelles and are required cell-autonomously for efficient production ill tempered gnome of neuronal exophers, giant ve

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